SESSION WATCH
Died HOUSE · SESSION 2026

No. HB 1381

Experimental Treatments for Terminal Conditions and Life-threatening Rare Diseases
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SPONSOR
Franklin
FILED BY
Gallop Franklin — District 8, Democrat [search donations]
EFFECTIVE
upon becoming a law
DIED IN
Health Professions & Programs Subcommittee

Filed under Healthcare.

PROVIDED SUMMARY

Experimental Treatments for Terminal Conditions and Life-threatening Rare Diseases; Authorizes licensed physicians to prescribe & eligible facilities to administer experimental treatments; requires approval of specified platform or master protocol by institutional review board; requires DOH to establish & maintain patient registry; requires DOH to annually publish specified report; encourages health insurers & health maintenance organizations to provide specified insurance coverage for experimental treatments; authorizes licensed physicians & eligible facilities to receive reimbursement for experimental treatments; requires manufacturers of experimental treatments to provide for specified temporary price concession; requires DOH to adopt by rule certain procedures for licensing of experimental treatment centers.

Full bill text →

Plain English Summary

AI-GENERATED
Lets physicians prescribe FDA-unapproved treatments to terminal and rare-disease patients.

Doctors licensed in Florida may now prescribe, and eligible hospitals may administer, treatments that have only cleared phase 1 safety trials and are not yet FDA-approved, to patients with a terminal condition or a rare disease affecting under 200,000 Americans.

Manufacturers must offer a temporary discounted price while a treatment remains unapproved, and the Department of Health sets a capped reimbursement rate for physicians and facilities, tied to registry compliance; the cap disappears once the FDA approves the treatment.

Patients bear the cost of experimental treatment themselves, and their estate is not liable for unpaid bills if they die using it. Manufacturers and providers acting in good faith cannot be sued for resulting harm, except for gross negligence or willful misconduct.

A doctor's license or Medicare certification cannot be pulled solely for recommending an experimental treatment. Insurers are only encouraged, not required, to cover these treatments, and may not refuse coverage solely because a treatment is experimental.

KEY PROVISIONS
§ 1 Physicians may prescribe unapproved experimental treatments majors. 499.0295

AILets a physician licensed under chapter 458 or 459 prescribe an experimental treatment, meaning a drug, biologic, device, or personalized genomic therapy that has cleared phase 1 trials but is not yet FDA-approved, to an eligible patient.

“A physician licensed under chapter 458 or chapter 459 may prescribe to an eligible patient an experimental treatment pursuant to this section.” bill text, line 141 →
§ 2 Facilities may administer treatments under an IRB protocol majors. 499.0295

AIAllows an eligible facility to administer an experimental treatment if it follows a platform or master protocol approved by an institutional review board and meets the patient-registry reporting requirements.

“An eligible facility may administer to an eligible patient an experimental treatment if such treatment is administered pursuant to a platform or master protocol” bill text, line 144 →
§ 3 Manufacturers must give a temporary discount on unapproved treatments majors. 499.0295

AIRequires a manufacturer of an experimental treatment to provide a temporary price concession, set by the department as a percentage of a recognized pricing benchmark, that expires once the FDA approves the treatment.

“A manufacturer of an experimental treatment shall provide for a temporary price concession, which price must be set by the department by rule” bill text, line 247 →
§ 4 No lawsuit against good-faith manufacturers or providers majors. 499.0295

AIBlocks a private lawsuit against a manufacturer, or against a person or entity involved in an eligible patient's care, for harm from an experimental treatment, as long as they acted in good faith with reasonable care; gross negligence and willful misconduct remain suable.

“This section does not create a private cause of action” bill text, line 279 →
§ 5 Physicians shielded from discipline for recommending treatment majors. 499.0295

AIBars a licensing board from revoking, denying renewal of, or suspending a physician's license, and bars a Medicare-certifying state agency from acting against a physician's certification, based solely on a recommendation to use experimental treatment.

“A licensing board may not revoke, deny renewal, suspend, or take any action against a physician's license issued under chapter 458 or chapter 459” bill text, line 270 →
§ 6 Reimbursement capped at a discounted rate below market price moderates. 499.0295

AILimits what physicians and facilities may be reimbursed for an experimental treatment to a discounted rate set by the department as a percentage of a recognized pricing benchmark, adjusted for registry compliance and reviewed every 2 years.

“Reimbursement for a prescribed or administered experimental treatment under this subsection may not exceed a discounted rate set by the department” bill text, line 232 →
§ 7 Insurers cannot deny coverage solely for being experimental, but owe none moderates. 499.0295

AIBars a health insurer or HMO from denying coverage solely because a treatment is experimental or FDA-unapproved, but the same section makes clear this creates no requirement to cover experimental treatment at all.

“may not deny insurance coverage based solely on a treatment being experimental or denied approval for general use by the FDA” bill text, line 217 →
§ 8 Public officials may not block access to experimental treatment moderates. 499.0295

AIProhibits a public official, employee, or state agent from denying or attempting to deny a patient's access to experimental treatment, though a physician's standard-of-care counseling or advice does not count as denial.

“may not deny or attempt to deny access to experimental treatment under this section” bill text, line 303 →
TIMELINE
3/13/2026
Died in Health Professions & Programs Subcommittee
1/15/2026
Now in Health Professions & Programs Subcommittee
1/15/2026
Referred to Health & Human Services Committee
1/15/2026
Referred to Health Care Budget Subcommittee
1/15/2026
Referred to Health Professions & Programs Subcommittee
1/13/2026
1st Reading (Original Filed Version)
1/9/2026
Filed
1 EARLIER →
STATUTES IT CHANGES
s. 499.0295
+10 / −0
s. 499.0295
+1954 / −0